which of the following is true of aaalac international?which of the following is true of aaalac international?
The production of polyclonal and monoclonal antibodies in animals is unnecessary in biomedical research. A. According to the Guide, social animals should be housed in pairs or groups whenever possible. C The criteria used for intervention in research studies to prevent unnecessary pain and distress are called "humane endpoint criteria" because they describe when it is time to: euthanize an animal to prevent suffering; discontinue a painful procedure; and/or remove an animal from a study. More than 60 prestigious scientific, educational and other professional organizations are members of AAALAC International and are represented on the Board of Trustees. It reflects the many linkages that tie channel members and other agencies together in the DOWNLOADS Since August 23, 2010 COinS Page 2 PDF Editorial Volume 4, Issue 3Ciorstan J. Smark PDF Book Review : Social and Environmental AccountingLee C. Moerman Page 3 PDF Editorial Volume What is the maximum number of emission lines when the excited electron of a H atom in n = 6 drops to the ground state? Assist with writing the basic science portions of a grant application. However, the latter should be performed under anesthesia and is not a preferred site because of the potential for damage to the eye when the technique is not done properly or when used repeatedly. To protect individuals who have frequent contact with animals in a research facility. B. IACUCs are not responsible for investigating allegations of mistreatment, misuse, or noncompliance, as it is the investigators role to do so. D. The names of the databases used, the date of the search, the years of citations accessed, and the search strategy. D. Food should be withheld prior to surgery, but not water. Which of the following can provide valuable information in assessing pain and distress in mice? D. To search for procedures that may replace the use of animals, reduce the number of animals used, or refine the methodology to minimize animal pain or distress. These institutions volunteer to participate in AAALAC's program, in addition to complying with the local, state and federal laws that regulate animal research. Thermal support is not required in mice during anesthesia. Major survival surgery on non-rodent mammals If the species involved is regulated by the USDA (for example, rabbits), then the entity producing the custom antibodies must also be registered or licensed by the USDA. The Council also appoints a roster of ad hoc consultants. Antibiotics should be routinely administered to avoid wound infection. A practicing scientist with experience in animal research, person who is not a scientist, person who is not affiliated with the organization, and public relations specialist. Which of the following sets of IACUC members are required by the AWA and/or PHS? To conduct voluntary evaluations of institutional animal care and use programs. A. D. Major non-survival surgery on non-rodent mammals. Which of the following statements is TRUE about injectable anesthetics compared with gaseous anesthetics used with mice? A change from non-survival to survival surgery The IACUC's activities to ensure compliance benefit whom? Which of the following would NOT be accepted by an IACUC as the sole justification for performing multiple major survival surgeries? A. Assist with writing the basic science portions of a grant application A. D. It is unacceptable to decapitate neonates with scissors, even with IACUC approval. BB creams are all-in-one beauty products that can With so many things to do in Miami, youll be able to create the perfect vacation package. D. Dogs must be provided additional exercise regardless of the floor area of the cage. Therefore, it is unnecessary to remove fetuses for euthanasia after the dam is euthanized (AVMA Guidelines 2013). B. Biosafety in Microbiological and Biomedical Laboratories, Recombinant DNA inserted into the genome of transgenic mice may NOT be covered by the NIH Guidelines for Research Involving Recombinant or Synthetic Nucleic Acid Molecules. Sedation causes vasodilation which helps make the tail vein easier to find. Methods for substance administration in rats and mice are outlined in which document? To provide assistance with alternatives and database searches. When picking up a mouse from a filter top cage, putting the wire bar lid sideways on the cage is helpful to: Reposition your grasp as you take the mouse out of the cage as it will tend to hold on to the wire bar lid. If the incision site on the skin is disinfected with iodine or chlorhexidine compounds, hair clipping is not necessary. The Animal Welfare Regulations (AWR) do not currently apply to which of the following animals? Studies in which animals are allowed to die without pain relief. D. Shares information with other regulatory agencies like U.S. Department of Agriculture (USDA) and Office of Laboratory Animal Welfare (OLAW). This is done through AAALAC's voluntary accreditation process in which research programs demonstrate that they meet the minimum standards required by law, and are also going the extra step to achieve excellence in animal care and use. Which of the following statements about postoperative care records is false? If the investigator believes the event is due to misuse, mistreatment, or noncompliance, the details of the incident should be reported to the IACUC (or use another reporting method recommended by their organization), so that the incident can be reviewed and investigated (if warranted). C. USDA regulations require that all mice be fasted prior to surgery. The correct dental formula of the mouse is: Which statement about the Occupational Health and Safety Program is false? The program started in 1965, when leading veterinarians and researchers organized the American Association for Accreditation of Labo A. Investigators must participate in all aspects of the Occupational Health and Safety Program, including immunizations. A. It is good to assume that procedures that are painful for humans are also painful for animals. Which statement concerning survival experimental surgery is FALSE? A. Nonaseptic surgical practices are acceptable when it can be shown that mice do not develop postsurgical infections. Some of the institutions that have earned AAALAC accreditation include the Sloan-Kettering Cancer Center, St. Jude Children's Research Hospital, The American Red Cross, and the National Institutes of Health. C. Solid bottom cages with contact bedding A veterinarian, practicing scientist with experience in animal research, person who is not a scientist, and person who is not affiliated with the organization. What is the recommended method for the production of monoclonal antibodies? Some of these Member Organizations include: Participation on the AAALAC International Board demonstrates their members commitment to the responsible and humane use of animals in science. Inspect the animal facilities at the time of each protocol submission Which of the following does not generally represent a good practice to follow when performing infectious disease work in animals? When assessing a client with partial-thickness burns over 60% of the body, which finding should the nurse report immediately? B. Lethal dose experiments in which animals are allowed to die without intervention. The organization and regulatory agencies only $$ In 1996, AAALAC changed its name to the Association for Assessment and Accreditation of Laboratory Animal Care International (AAALAC International). Which of the following falls within the range of the total blood volume of adult mice? B. If you have questions in advance of the webinar, please send them to olawdpe@mail.nih.gov. Julie S Snyder, Linda Lilley, Shelly Collins, Explain the important distinctions between **periods and groups of the periodic table**. Which statement is true about mice in the age range of 6-10 days? The Johns Hopkins Center for Alternatives to Animal Testing (CAAT), the Institute for In Vitro Sciences, and the European Center for Validation of Alternative Methods (ECVAM) are primarily interested in what area? The library service used to perform the search, the date of the search, and the key words used. AAALAC stands for the Association for Assessment and Accreditation of Laboratory Animal Care. More than 850 companies, universities, hospitals, government agencies and other research institutions in 36 countries have earned AAALAC accreditation, demonstrating their commitment to responsible animal care and use. Non-USDA regulated species are never required to be placed in a pain/distress category. In the mouse, IP injection should proceed only after aspiration has shown that the needle is properly positioned. It provides a mechanism for peer evaluation of animal care and use programs B. D. Postoperative analgesia should be discussed with and approved by a veterinarian. A. C. Once respiration stops in mice euthanatized with carbon dioxide, it is safe to assume that death has occurred, and mice may be placed in an airtight bag and transferred to the necropsy refrigerator. B. Pre-operative planning is very important. (1) If, in the opinion of the attending veterinarian, it is inappropriate for certain dogs to exercise because of their health, condition, or well-being, the dealer, exhibitor, or research facility may be exempted from meeting the requirements of this section for those dogs(2) A research facility may be exempted from the requirements of this section if the principal investigator determines for scientific reasons set forth in the research proposal that it is inappropriate for certain dogs to exercise." Post-operative analgesics should be used and daily post-procedural monitoring done by personnel familiar with rodent behavior. Which of the following statements about caging for mice reflect the information that is in the Guide for the Care and Use of Laboratory Animals? Mouse urine and pelt proteins are an allergic hazard to people. Non-vertebrates, laboratory mice, and laboratory rats. D. Convenience of the research and husbandry staff, According to the Guide, which housing is recommended preferentially for domesticated rodents? Which activity would place a study in pain category B? Which is a TRUE statement below regarding assessment of pain or distress in mice: D. Mice have a low metabolic rate. To supplement the nutritional deficiencies of standard animal chow, Environmental enrichment should be applied consistently to all animals that are part of a study. A total number of 15 lines (5 + 4 + 3 + 2 + 1) will be obtained in this Who better to ask than your local auto body shop? B. Non-survival Which statement does not apply to experimental surgery on animals? In the 1950s, the Professional Standards Committee of the Animal Care Panel (ACP), now the American Association for Laboratory Animal Science (AALAS), recognized a need for assuring the general public that laboratory animal research was conducted on a professional level, and that standard procedures were applied. The Council on Accreditation is the group responsible for evaluating animal programs and determining their accreditation status. C A mandated IACUC function is to conduct reviews of the animal care and use program on a semiannual basis. Enrollment in the institutional Occupational Health and Safety program is mandatory before working with animals. Which of the following is NOT an example of reduction per the three Rs of Russell and Burch? C. The veterinarian cannot exempt an animal, even for medical reasons. Which of the following organizations must comply with the PHS Policy when utilizing vertebrate animals for research, teaching, or testing? Lethal dose experiments in which animals are allowed to die without intervention. A public relations specialist, veterinarian, person who is not a scientist, and person who is not affiliated with the organization. Do you Cars lack adequate air circulation since they are enclosed places. B. The Council is divided into North American, European and Pacific Rim Sections. D. Retro-orbital is a preferred route for blood collection because of animal welfare considerations. C. A change in personnel. A. Unsourced material may be challenged and removed. The Association for Assessment and Accreditation of Laboratory Animal Care International, or AAALAC, is a private, nonprofit organization that promotes the humane treatment of animals in science through voluntary accreditation and assessment programs. What is generally a superior anesthesia choice for mice undergoing major surgical procedures? Participation as a Member Organization demonstrates commitment to the responsible and humane use of animals in science. A. D. Those organizations that accept Public Health Service (PHS) or National Science Foundation (NSF) funding. B According to the AWR (3.81.d. 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